TABLE 2.

Bivariate analysis of the association between plc gene genotypes and clinical characteristics using GEE

plc gene genotypeClinical characteristic
Extrathoracic TB involvement (n = 682)Cavitation in the lungs (n = 584)Sputum smear positive (n = 586)
No. with TTBaNo. with ETTBbOR (95% CI)NoYesOR (95% CI)No. negativeNo. positiveOR (95% CI)
plcD genotypes
plcD wild type405441.00 (referent)2431441.00 (referent)2281621.00 (referent)
plcD mutant2992.86 (1.32-6.19)21110.88 (0.41-1.89)22100.64 (0.30-1.39)
plcD and adjacent gene, mutant group170251.35 (0.82-2.23)104610.99 (0.68-1.44)85791.31 (0.91-1.89)
plcABC genotypes
plcABC wild type546691.00 (referent)3261971.00 (referent)2982271.00 (referent)
One of plcABC mutant4071.38 (0.58-3.30)28130.77 (0.40-1.48)24170.93 (0.50-1.74)
Two of plcABC mutant611.32 (0.15-1.68)520.66 (0.16-2.67)520.52 (0.13-2.13)
plcABC all mutant1210.66 (0.08-5.30)940.74 (0.27-2.00)850.82 (0.25-2.66)
  • a TTB, thoracic tuberculosis.

  • b ETTB, extrathoracic tuberculosis.