TABLE 1.

Antibiotic resistance patterns and genotypic analysis (MLST, spa types) of Staphylococcus aureus isolates in Ibadan, Nigeria, 2006 to 2007

ST (no. of isolates)agr type(s) (no. of isolates)spa type(s)Antibiotic resistance pattern; agr type (no. of isolates)aToxin genes
ST5 (76)I (39), II (37)t311PEN, SXT, TET; agr I and II (37)sea, seb, sec, seg, tst, lukED, luk-PV,d hlgA
PEN, SXT, TET, CIP; agr I (16)
PEN, SXT, TET, ERY; agr II (19)
ST7 (45)I (33), II (12)t091PEN; agr I and II (10)sea, seg, lukED, luk-PV, hlgA
PEN, SXT; agr I (18)
PEN, SXT, TET; agr I (16)
ST121 (38)IVt159, t314PEN, SXT (12)seb, seg, lukED, luk-PV, hlgA
PEN, SXT, TET (23)
ST250b (35)I (30), IV (5)t194, t292PEN, OXA, TET, CIP, GEN; agr I (23)seb, tst, lukED, hlgA
PEN, OXA; agr IV (5)
ST88 (33)III (33)t186PEN, OXA, SXT (32)seg, luk-PV, hlgA, hlgB
PEN, OXA (1)
ST30 (30)IIIt318PEN, SXT (22)seg, tst, lukED, luk-PV, hlgA, hlgB
PEN, SXT, TET (4)
ST8 (25)It064, t068PEN, SXT, TET, CIP, GEN (12)sea, seb, seg, tst, lukED, luk-PV, hlgA
PEN, SXT, TET (6)
ST1 (22)IIIt273PEN (20)tst, luk-PV, hlgA
ST15 (10)IIt084, t085PEN, SXT, TET (8)lukED, hlgA
ST508 (9)INTcSensitive (9)seb, sec, tst, hlgA, hlgB
ST80 (8)IIIt359PEN, SXT, TET (8)tst, lukED, luk-PV, hlgA
ST241 (7)It037PEN, OXA, TET, CIP, GEN, ERY, CLI (7)lukED, hlgA
ST25 (5)It353PEN, SXT (5)sec, seg, lukED
ST72 (3)It537PEN, TET (3)seg, lukED, hlgA
  • a The major frequent antibiotic resistance patterns are given for each sequence type (PEN, penicillin; OXA, oxacillin; TET, tetracycline; CIP, ciprofloxacin; ERY, erythromycin; GEN, gentamicin; CLI, clindamycin).

  • b ST250 represents both MRSA and MSSA isolates.

  • c NT, not typeable.

  • d Detection of this gene in this strain was rare.