TABLE 1.

Results of molecular typing of S. pyogenes isolates harboring emm12

IsolateClinical sign(s) and/or symptom(s)aSite(s) of isolationRAPD patternbvir regulon patterndrs allele
AB
AC-1460Cellulitis, STSSBlood, woundII1drs12.04
AC-1574STSS, necrotizing fasciitisBloodII1drs12.01
AC-1575Erysipelas, STSSBloodII1drs12.01
AC-1780Nasal carriageNasopharynxII1drs12.03
AC-1781Nasal carriageNasopharynxII1drs12.01
AC-1985OsteomyelitisJoint fluidD*I2drs12.01
AC-2080SIDSLung tissueID**1drs12.03
AC-2152Pharyngitis, rheumatic feverNasopharynxII1drs12.01
AC-2272STSSBloodII1drs12.03
AC-2276SIDSTracheaII1drs12.02
AC-2352PharyngitisNasopharynxII5drs12.02
AC-2353PharyngitisNasopharynxII5drs12.01
AC-2416BacteremiaBloodII1drs12.01
AC-2417BacteremiaBloodII1drs12.01
AC-2432PharyngitisNasopharynxII5drs12.02
AC-2445PharyngitisNasopharynxII4drs12.02
AC-2874BacteremiaBloodII1drs12.01
AC-3024BacteremiaBloodII1drs12.01
AC-3292Surgical wound infection, abscessWoundII1drs12.02
AC-3297Abscess, cellulitis, STSSWoundII1drs12.02
AC-3681SIDSMeninges, pleuraII1drs12.01
AC-3735Necrotizing fasciitis, myositisBlood, woundII1drs12.01
AC-3854Septic arthritis, necrotizing fasciitisJoint fluidII1drs12.03
AC-3954SepsisBloodID**1drs12.01
AC-3959Necrotizing fasciitisPleural fluidII2drs12.01
AC-3967SepsisBloodID**1drs12.01
AC-4075Necrotizing fasciitisBloodII1drs12.01
AC-4098Recurrent tonsillitisNasopharynxII3drs.NS488
  • a STSS, streptococcal toxic shock syndrome; SIDS, sudden infant death syndrome.

  • b RAPD patterns were obtained by using either primer H2 (A) or primers p14 and p17 (B). I, pattern indistinguishable; D*, pattern lacking three distinct bands; D**, pattern with one aberrant band out of 15 distinct bands.