TABLE 2.

Overall interpretive agreement between results of fluconazole and voriconazole agar-based susceptibility tests and of standard 48-h BMD reference tests for 235 C. glabrata isolates

Antifungal agentMethod and mediuma% of isolates by categoryb% of discrepant resultsc% Categorical agreementd
SS-DDRMinorMajorVery major
FluconazoleBMD57367
ET-RPG32541446.01.7052.3
ET-MBE44441236.61.7061.7
Disk902834.900.464.7
VoriconazoleBMD937
ET-RPG9282.62.694.8
ET-MBE9371.72.196.2
Disk9460.91.797.4
  • a See footnote a of Table 1 for definitions of BMD, ET-RPG, ET-MBE; disk, disk diffusion test with fluconazole (25-μg disk) and voriconazole (1-μg disk).

  • b Percentage of isolates classified in the different susceptibility categories. See Materials and Methods for definitions.

  • c Percentage of test results with minor, major, or very major discrepancies compared to the results of the reference BMD method at 48 h. See Materials and Methods for definitions.

  • d Agreement rates reflect the percentage of isolates classified in the same category by both the agar-based (Etest and disk) and the reference BMD methods.