Concordance between phenotype (MIC determined by Etest) and genotype (sequencing or real-time PCR) for H. pylori strains included in the study

H. pylorianrrl genotypegyrA genotype
Wild typeMissense mutationNo dataWild typeMissense mutationNo data
Phase 1
    Development panel H. pylori strains126
Phase 2
    Clinical H. pylori strains92
    Gastric biopsy specimens105
  • a CLA, clarithromycin; FQ, fluoroquinolone; S, susceptible; R, resistant.

  • b Clarithromycin MIC, 2 μg/ml.

  • c Sixteen strains harbored a Thr87, which confers fluoroquinolone susceptibility.