TABLE 3.

Associations between other putative virulence genes of MRSA isolates and clinical outcome

Category and geneNo. (%) of MRSA patients (n = 522)No. of cured patients/total no. of patients (%) with indicated gene statusPa
AbsentPresent
Adhesins
    fnbA471 (90.2)39/51 (76.5)433/471 (91.9)0.015
    clfA521 (99.8)1/1 (100.0)471/521 (90.4)1.000
    clfB494 (94.6)22/28 (78.6)450/494 (91.1)0.107
    cna34 (6.5)446/488 (91.4)26/34 (76.5)0.036
    spa522 (100.0)0/0472/522 (90.4)1.000
    sdrC503 (96.4)13/19 (68.4)459/503 (91.3)0.026
    sdrD502 (96.2)18/20 (90.0)454/502 (90.4)1.000
    sdrE508 (97.3)11/14 (78.6)461/508 (90.7)0.258
    bbp516 (98.9)5/6 (83.3)467/516 (90.5)0.705
    ebpS522 (100.0)0/0472/522 (90.4)1.000
    map-eap455 (87.2)53/67 (79.1)419/455 (92.1)0.016
    fnbB497 (95.2)20/25 (80.0)452/497 (90.9)0.191
Toxins
    eta91 (17.4)394/431 (91.4)78/91 (85.7)0.254
    etb1 (0.2)471/521 (90.4)1/1 (100.0)1.000
    tst166 (31.8)323/356 (90.7)149/166 (89.8)1.000
    sea51 (9.8)429/471 (91.1)43/51 (84.3)0.258
    seb3 (0.6)469/519 (90.4)3/3 (100.0)1.000
    sec11 (2.1)462/511 (90.4)10/11 (90.9)1.000
    sed27 (5.2)452/495 (91.3)20/27 (74.1)0.036
    see8 (1.5)466/514 (90.7)6/8 (75.0)0.299
    seg55 (10.5)429/467 (91.9)43/55 (78.2)0.016
    seh7 (1.3)467/515 (90.7)5/7 (71.4)0.258
    sei64 (12.3)422/458 (92.1)50/64 (78.1)0.015
    sej24 (4.6)456/498 (91.6)16/24 (66.7)0.015
    hlg521 (99.8)1/1 (100.0)471/521 (90.4)1.000
Others
    efb520 (99.6)2/2 (100.0)470/520 (90.4)1.000
    icaA506 (96.9)15/16 (93.8)457/506 (90.3)1.000
    chp483 (92.5)33/39 (84.6)439/483 (90.9)0.408
    V8514 (98.5)5/8 (62.5)467/514 (90.9)0.093
    SCCmec type IV466 (89.3)45/56 (80.4)427/466 (91.6)0.042
    agr group II vs all others40 (7.7)442/482 (91.7)30/40 (75.0)0.016
  • a P values are adjusted for multiple comparisons to control the false-discovery rate for the family of all tests within this table to 20%.