TABLE 2.

Relation of demographic, clinical, and outcome variables for patients with BSI to time to notificationa

VariableTime (h) to notification
<24 (n = 546)24-47 (n = 275)48-71 (n = 69)≥72 (n = 27)
Hospital
    Lahey Clinicc255 (55)146 (32)45 (10)15 (3)
    UIHC291 (64)129 (28)24 (5)12 (3)
Mean age (yr)60 (17-98)59 (17-91)63 (23-91)63 (27-87)
Female255 (63)100 (25)37 (9)10 (2)
Male291 (56)175 (34)32 (6)17 (3)
Admitting servicec
    General medicine283 (64)112 (25)34 (8)12 (3)
    Hematology/oncology95 (66)38 (26)8 (5)2 (1)
    General surgery47 (57)29 (35)3 (4)3 (4)
    Cardiology25 (61)11 (27)5 (12)0
    Neurosurgery12 (46)13 (50)01 (4)
    Solid organ Transplant18 (58)7 (23)4 (13)2 (6)
    Neurology5 (29)10 (59)2 (12)0
    Bone marrow Transplant17 (48)14 (40)3 (9)1 (3)
    Cardiovascular surgery7 (47)7 (47)1 (7)0
    Urology11 (44)8 (32)4 (16)2 (8)
    Vascular surgery4 (44)4 (44)01 (11)
    Orthopedic surgery4 (33)5 (42)2 (17)1 (8)
    Obstetrics and gynecology6 (75)2 (25)00
    Burns3 (37)3 (37)1 (12)1 (12)
    Other9 (37)12 (50)2 (8)1 (4)
Location at T0b
    ICU227 (37)284 (46)69 (11)31 (5)
    Floor498 (43)457 (40)122 (11)80 (7)
Fever within 24 h of T0b383 (62)175 (28)44 (7)15 (2)
No fever161 (54)100 (34)25 (8)12 (4)
Temperature at T0b
    <36°C25 (57)10 (23)7 (16)2 (5)
    36-38.5°C271 (56)158 (32)41 (8)17 (3)
    >38.5°C250 (65)107 (28)21 (5)8 (2)
Endotracheal tube at T0d60 (46)53 (40)15 (11)3 (2)
No endotracheal tube486 (62)222 (28)54 (7)24 (3)
White blood cell count at T0
    <1,00070 (57)40 (33)11 (9)1 (1)
    1,000-4,49953 (69)17 (22)6 (8)1 (1)
    4,500-12,499203 (59)98 (28)31 (9)14 (4)
    12,500-19,999133 (58)77 (34)11 (5)8 (3)
    ≥20,00087 (61)43 (30)10 (7)3 (2)
Charlson index score:
    0203 (59)109 (32)21 (6)11 (3)
    184 (56)50 (33)13 (9)3 (2)
    2130 (65)50 (25)17 (9)3 (2)
    3, 4, 587 (57)45 (30)11 (7)6 (4)
    ≥642 (56)21 (28)7 (9)4 (5)
Hospital acquired257 (55)163 (35)36 (8)14 (3)
Community acquired289 (65)112 (25)33 (7)13 (3)
Ever admitted or transferred to ICU239 (56)136 (32)37 (9)11 (3)
Mean no. of total blood culturesd4.87 (0-20)6.03 (0-20)6.07 (0-20)5.96 (1-20)
Mean no. of blood cultures with same organismb1.101.051.040.96
Polymicrobial61 (60)30 (30)7 (7)3 (3)
Monomicrobial485 (59)245 (30)62 (8)24 (3)
Length of stay (days)c18.1 (0-144)22.2 (0.1-135)21.8 (0.9-102)26.6 (0.3-115)
Length of stay from T0 to discharge (days)b13.1 (0-101.2)14.9 (0-117.0)16.6 (0-101.1)18.2 (0.4-85.6)
Total hospital charges (dollars)c59,15084,02273,82092,305
Death128 (60)61 (28)17 (8)8 (4)
  • a Unless otherwise specified, values in table represent the numbers of patients. Single values in parentheses indicate percentages, and values separated by dashes indicate ranges.

  • b P < 0.05.

  • c P < 0.01.

  • d P < 0.001.