TABLE 2.

Performance of RT-PCR assays for rapid detection of CoV associated with SARS

Specimens (no.)No. of specimens testedSeroconversionaNo. of specimens positive by RT-PCR assay
WHO-HKUWHO-HamburgBoth WHO-HKU and WHO-Hamburg
Clinically suspected SARS
    Nasopharygneal aspirate specimens (124)72+444943
52000
    Throat swab specimens (65)54+353933
11000
    Urine specimens (95)78+394239
17000
    Stool specimens (19)19+111211
Controls
    Nasopharygneal aspirate specimens22bND000
    Stool specimens21cND000
  • a A fourfold rise or more in antibody titer against CoV was considered seroconversion (+). ND, not done.

  • b Samples positive for other viral pathogens included nine samples positive for influenza virus A, one sample positive for influenza virus B, six samples positive for adenovirus, and six samples positive for RSV by immunofluorescence (2).

  • c No intestinal pathogens detected.