TABLE 2.

Influence of the clinical presentation, presence of antibodies, and age of serum on the LCN-PCR results

VariableValue for positive LCN-PCR group (n = 18)Value for negative LCN-PCR group (n = 82)Univariate analysisMultivariate analysis, P value
P valueOdds ratio (range)
Sex ratio (M/F)a1.61.70.80.9 (0.3-2.6)0.7
Mean age ± standard deviation (yr)46.1 ± 12.547.9 ± 18.90.80.8
% of patients with:
    Chills55.546.30.51.4 (0.5-4.0)0.8
    Headache61.153.60.61.3 (0.5-3.8)0.9
    Myalgias50.059.70.40.7 (0.2-1.9)0.5
    Pneumonia16.77.30.22.5 (0.5-11.2)0.3
    Liver involvement50.056.10.60.8 (0.3-2.1)0.6
    Presence of antibodies to C. burnetii11.145.1<10−20.2 (0.06-0.8)0.1
Mean time interval between onset and serum sampling ± SD (days)12.2 ± 14.219.2 ± 19.00.10.8
% of patients for which:
    Sera were sampled ≤7 days after onset of symptoms44.442.70.91.1 (0.3-3.3)0.9
    Sera were sampled ≤10 days after onset of symptoms55.548.70.61.3 (0.4-4.1)0.8
    Sera were sampled ≤14 days after onset of symptoms88.960.90.025.1 (1.02-34.6)0.9
  • a M/F, male/female.