TABLE 9.

Fluconazole and voriconazole agar disk gradient MICs for C. albicansa

Country (no. of sites in 2001)FluconazoleVoriconazole
MIC50MIC90nMIC50MIC90n
Argentina (2)0.321.846070.0190.128471
Australia (1)0.5364.98210.0190.78921
Belgium (2)<0.250.68450<0.0080.040372
Brazil (1)<0.251.44446<0.0080.061333
Canada (2)0.411.12870.0190.08587
China (2)0.873.90930.0530.19692
Colombia (2)1.4410.583900.0821.118369
Czech Republic (2)0.683.909380.0460.350720
Ecuador (1)2.3742.112500.096>4.80174
France (4)0.873.904560.0460.262274
Germany (5)<0.251.122990.0140.061299
Greece (1)<0.251.2888<0.0080.06188
Hungary (5)0.8710.581,0160.0611.496873
Italy (7)0.685.006960.0300.262696
Malaysia (1)0.413.041,2460.0460.350521
Mexico (2)1.124.45230.0821.51218
The Netherlands (1)0.321.121,2040.0140.0611,204
Poland (1)0.411.121700.0460.14645
Russia (1)3.0491.22110.0610.2624
Slovakia (4)0.875.003910.0460.977391
South Africa (5)0.412.371,0490.0190.1091,010
South Korea (1)0.531.844260.0260.146347
Spain (2)0.413.049690.0140.146966
Switzerland (2)0.411.841610.0190.082161
Taiwan (3)1.446.423990.0820.625394
Thailand (2)0.682.701300.0340.262129
Turkey (2)0.683.471410.0460.350111
United Kingdom (3)0.533.049770.0190.146692
United States (9)0.533.046760.0260.196682
Venezuela (1)1.445.001200.0710.35098
  • a All specimen types were tested, all locations were in hospitals and only 2001 data are shown. Test range: fluconazole, <0.25 to >165 μg/ml; voriconazole, <0.008 to >4.8 μg/ml.