TABLE 2.

Distribution and comparison of serum HBV DNA levels from subjects in the North American trial and subjects in the Asian trials by range of log10 copies per milliliter determined by COBAS-AM and Genostics assays

Range of HBV DNA levels (log10 copies/ml) based on COBAS-AM assayNo. of specimens (n = 1,695)Mean (SEM) HBV DNA level (log10 copies/ml)Mean (SEM) difference in HBV DNA levels (log10 copies/ml) between assays
COBAS-AM assayGenostics assay
21132.34 (0.03)
3973.24 (0.01)
41314.51 (0.02)
53235.51 (0.02)
61746.46 (0.03)5.74 (0.03)−0.71 (0.03)
71707.53 (0.02)6.29 (0.05)−1.24 (0.04)
83838.58 (0.02)7.10 (0.02)−1.48 (0.02)
92869.26 (0.01)7.56 (0.02)−1.70 (0.02)
101410.22 (0.08)7.91 (0.11)−2.31 (0.15)
11411.11 (0.06)7.91 (0.10)−3.20 (0.07)