TABLE 2.

Global distribution and frequencies of the MLSTs in the period from 1990 to 1999a

MLSTAlleles% Distribution by country and periodbNo. of isolates (n = 164)
The NetherlandsUnited StatesFinland, 90-99 (n = 27)Italy, 90-99 (n = 10)Japan, 90-99 (n = 13)
Prevac (n = 11)90-99 (n = 85)Prevac (n = 8)90-99 (n = 10)
MLST-1 ptxS1D, ptxS3A, tcfA2 451258
MLST-2 ptxS1B, ptxS3A, tcfA2 55450106923
MLST-3 ptxS1A, ptxS3A, tcfA2 251089401552
MLST-4 ptxS1A, ptxS3A, tcfA3 32116036
MLST-5 ptxS1A, ptxS3B, tcfA2 38601541
MLST-7 ptxS1A, ptxS3A, tcfA5 101
MLST-8 ptxS1B, ptxS3B, tcfA2 101
MLST-9 ptxS1E, ptxS3A, tcfA1 252
  • a For the Netherlands and the United States strains from the prevaccination period have been included.

  • b Prevac, prevaccination period; 90-99, period from 1990 to 1999. n, number of isolates.