TABLE 2.

Clinical data, plasmid profiles, and ribotypes of the 10 DHA-1-producing K. pneumoniae isolates

Patient no.Age (yr)/sexIsolateCollection date (day/mo/yr)SourceType of infectionWardaDuration between admission and:Comorbid conditionsbPrevious medicationcOutcomePlasmid profileRibotype (EcoRI/BstEII)
Isolation (days)Previous hospitaliza- tion (mo)
155/M38726/04/99WoundWoundSurgery 7A14Fractures, head injuryCEF, AMC, CMZRecoveredP1E1/B1
274/M41606/05/99UrineUrinary tractReh11Cirrhosis, spine injury, lung cancerCEFDeathP2E2/B2
381/F149022/01/00SputumColonizationSurgery 7A23Fractures, head injuryCFZ, IPMDeathP5E5/B5
471/M159622/02/00SputumColonizationCCU32CAD, acute renal failureOXA, TZP, CMZDeathP5E5/B5
535/M19709/10/00AscitesPeritonitisSurgery 6B20Cirrhosis, intra-abdominal bleeding, acute renal failureCEF, CTX, CRODeathP6E3/B3
669/M27402/12/00WoundWoundER01DM, ESRDPIPRecoveredP6E3/B3
777/F28106/12/00UrineUrinary tractOPD05ESRD, stroke, HTN, ParkinsonismAMCDeathP6E3/B3
882/F32525/12/00SputumColonizationER04ESRD, head injuryUnknownDeathP3E4/B4
978/F39713/04/01UrineUrinary tractMICU34Tetanus, pneumoniaPIP, AMC, CEF, CMZRecoveredP1E6/B6
1074/M106727/08/01BloodBacteremiaER11DM, ESRD, strokeCEF, CTXRecoveredP4E7/B7
  • a Reh, rehabilitation; CCU, critical care unit; ER, emergency room; OPD, outpatient department; MICU, medical intensive care unit.

  • b CAD, coronary artery disease; DM, diabetes mellitus; ESRD, end-stage renal disease; HTN, hypertension.

  • c Only β-lactam agents are listed. AMC, amoxicillin-clavulanic acid; CEF, cephalothin; CFZ, cefazolin; CMZ, cefmetazole; CTX, cefotaxime; CRO, ceftriaxone; IPM, imipenem; OXA, oxacillin; PIP, piperacillin; TZP, piperacillin-tazobactam.