TABLE 5.

Cross-resistance of C. albicans isolates to licensed and investigational triazolesa

Antifungal agentSuscep- tibility categorybNo. of isolatesCumulative % inhibited at MIC (μg/ml):
0.120.250.51248
VoriconazoleRR3702.710.818.937.840.540.5
RS382.626.355.394.7100
RavuconazoleRR3212.518.825.040.643.846.946.9
RS3850.089.597.4100
  • a Adapted from reference 47 with permission.

  • b RR, fluconazole MIC ≥64 μg/ml and itraconazole MIC ≥1 μg/ml; RS, fluconazole MIC ≥64 μg/ml and itraconazole MIC ≤0.12 μg/ml.