TABLE 6.

Most common virulence profiles of STEC strains and their distribution by the clinical pictures of 170 subjects

Virulence profilePhenotype and genotypeTotal no. of subjects (n = 170a)No. of subjects with:Other bacterial characteristics
HUS or TTP (n = 20b)Bloody diarrhea (n = 77c)Nonbloody diarrhea (n = 37)Asymptomatic (n = 26d)Not known (n = 10)eae positiveEhly positiveStx titer of ≥128
P1O157:H7:PT2:stx2:stx2c559e30871555555
P2O145:H28/H:stx273b3c010763
P3O157:H7/H:PT88:stx241b0012400
P4O157:H7:PT49:stx2:stx2c1015220101010
P5O157:H7:PT2:stx2413000444
P6O103:H2/H:stx1130561112135
P7O157:H7/H:PT8:stx1 and stx2 or stx2 variantf804211865
P8O157:H7:PT4:stx2703310777
P9O26:H11/H:stx1704021761
P10O157:H7:PT4:stx2:stx2c504100555
Other O1571805c1012181413
Other non-O157356g12h5i10d,j2k141811
  • a Three patients had infections with STEC O157 and non-O157 strains (the number of isolates is then 173).

  • b One patient had a simultaneous infection with O157:H:PT88:stx2 and O145:H28:stx2 (the number of isolates is then 21).

  • c One patient had a simultaneous infection with O157:H:PT88 lacking stx and O145:H28:stx2 (the number of isolates is then 78).

  • d One patient had consecutive infection with O102:H7:undigestible and O Rough:H18:undigestible (the number of isolates is then 27).

  • e Two patients in the age group of 1 to 5 years died.

  • f stx2 variants were stx2c (five strains), stx2vhb (two strains), and stx2 and stx2vhb (one strain).

  • g The corresponding virulence profiles were (one strain each) OX174:H21:stx2c, O Rough:H4:stx2c, O101:H:stx2, O Rough:H49:stx2c, O107:H27 lackin g stx, and O2:H29:undigestible.

  • h The corresponding virulence profiles were (one strain each) O156:H25:stx1, O15:H:stx1, OX181:H49:stx2:stx2c, OX174:H21:stx2vhb, OX174:H2:stx2vhb, O165:H25:stx2, O103:H2:stx2, O91:H40:stx1:stx2c, O Rough:H:stx1, O Rough:H:stx2d-Ount, O8:H9:stx2vhb, and O20:H7:stx2c.

  • i The corresponding virulence profiles were (one strain each) O76:H19:stx2d-Ount, O15:H:stx2, O91:H21:stx2:stx2vhb, O111:H8:stx1 , ONT:H33:weak positive in PCR.

  • j The corresponding virulence profiles were O Rough:H2:stx2 (one strain), O15:H:stx1 (one strain), O103:H2:stx2 (two strains), O Rough:H21:weak positive in PCR (one strain), O Rough:H4:stx2 (two strains), O116:H21:stx2 (one strain), O102:H7:undigestible (one strain), and O Rough:H18:undigestible (one strain).

  • k The corresponding virulence profiles were O43:H2:stx1 and O Rough:H:stx1.