Table 3.

Cross-reactivity serum panela tested by seven treponemal assays and the RPR assay

Potentially cross-reactive analyte or condition (no. of sera tested)No. (%) of sera testing positive or equivocal by:
BioPlex syphilis IgGFTATrep-Chek IgGTP-PATrep-SureTrep-IDViraBlot IgGRPR
HSVb IgG (5)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
HSV IgM (2)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
EBV IgG (5)0 (0)1 (20)0 (0)0 (0)0 (0)0 (0)0 (0)1 (20)
EBV IgM (5)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
Rheumatoid factor (3)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
Heterophile antibodies (5)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
Pregnancy (28)0 (0)1 (3.6)0 (0)0 (0)0 (0)1 (3.6)1 (3.6)c0 (0)
  • a The cross-reactivity test panel comprised 53 sera.

  • b HSV, herpes simplex virus.

  • c This result was equivocal by the ViraBlot IgG assay.