TABLE 1

Comparative performance of smear microscopy, Xpert MTB/RIF, and Xpert Ultra using culture as the gold standard (n = 196 specimens)

TestM. tuberculosis detection
% sensitivity (95% CI)% specificity (95% CI)
All culture-positive specimens (n = 47)Smear-positive/culture-positive specimens (n = 23)Smear-negative/culture positive specimens (n = 24)All culture-negative specimens (n = 149)
Smear microscopy48.94 (35.28–62.76) 23/47100 (97.49–100) 149/149
Xpert MTB/RIF82.98 (69.86–91.11) 39/47100 (85.69–100) 23/2366.67 (46.71–82.03) 16/2497.32 (93.30–98.95) 145/149
Xpert Ultra95.74 (85.75–99.24) 45/47100 (85.69–100) 23/2391.67 (74.15–98.52) 22/2496.64 (92.39–98.56) 144/149