TABLE 1

Identification results and performance of detection for organisms targeted by the ePlex BCID panels compared to culture

ePlex panel (no. of cartridges tested with valid results) and positive targets by ePlexIsolate identification on culture (n)Isolates not detected by ePlex (n)Sensitivity (%)Specificity (%)
BCID-GP (93)
    Staphylococcus, S. aureusS. aureus (14)14/14 (100)79/79 (100)
    Staphylococcus, S. epidermidisS. epidermidis (20)S. epidermidis (1)20/21 (95)72/72 (100)
    StaphylococcusbS. haemolyticus (5)40/40b (100)53/53b (100)
    Streptococcus, S. pyogenesS. pyogenes (1)1/1 (100)92/92 (100)
    Streptococcus, S. agalactiaeS. agalactiae (3)3/3 (100)90/90 (100)
    Streptococcus, S. pneumoniaeS. pneumoniae (9)9/9 (100)84/84 (100)
    Streptococcus, S. anginosus groupS. anginosus (2), S. intermedius (1)3/3 (100)90/90 (100)
    StreptococcusbS. gallolyticus (4), S. dysgalactiae (3), S. mitis (3), S. lutetiensis (1)27/27b (100)66/66b (100)
    Enterococcus, E. faecalisE. faecalis (17)17/17 (100)76/76 (100)
    Enterococcus, E. faeciumE. faecium (13)13/13 (100)80/80 (100)
    EnterococcusbNone30/30b (100)63/63b (100)
    CorynebacteriumC. mucifaciens (1)1/1 (100)92/92 (100)
    Listeria, L. monocytogenesL. monocytogenesa (1)1/1 (100)92/92 (100)
    LactobacillusNot cultured (1)NAc92/93 (99)
    Pan-Gram negativeE. coli (3), P. mirabilis (1), Bacteroides caccae (1)E. coli (1)5/6 (83)87/87 (100)
BCID-GN (122)
 E. coliE. coli (59)59/59 (100)63/63 (100)
 K. pneumoniaeK. pneumoniae (14)14/14 (100)108/108 (100)
 K. oxytocaK. oxytoca (5)5/5 (100)117/117 (100)
 E. cloacae complexE. cloacae (5), E. asburiae (1)6/6 (100)116/116 (100)
    Enterobacter (non-cloacae complex)E. aerogenes (3)3/3 (100)119/119 (100)
    CitrobacterC. koseri (1)1/1 (100)121/121 (100)
    Proteus, P. mirabilisP. mirabilis (8)8/8 (100)114/114 (100)
    M. morganiiM. morganii (2)2/2 (100)120/120 (100)
    Serratia, S. marcescensS. marcescens (3)3/3 (100)119/119 (100)
    SerratiabS. liquefaciens (1)4/4 (100)b118/118 (100)b
 P. aeruginosaP. aeruginosa (13)P. aeruginosa (1)13/14 (93)108/108 (100)
 S. maltophiliaS. maltophiliaa (2)2/2 (100)120/120 (100)
 B. fragilisB. fragilisa (4)4/4 (100)118/118 (100)
 F. necrophorumNot cultured (4)NA118/122 (97)
    Pan-Gram positiveE. faecalis (3), E. faecium (1), E. avium (1), S. anginosus (1), S. gallolyticus (1), not cultured (2)7/7 (100)112/114 (98)
BCID-FP (7)
 C. albicansC. albicans (2)2/2 (100)5/5 (100)
 C. glabrataC. glabrata (3)3/3 (100)4/4 (100)
 C. parapsilosisC. parapsilosis (1)1/1 (100)6/6 (100)
  • a Including one isolate recovered at secondary subculture of frozen blood culture sample aliquots.

  • b Performance calculated including all isolates belonging to the targeted genus.

  • c NA, not applicable.