Characteristics of serum panels used in this study

Serum testing panelRT-PCRFRµNT90CountryYr
VirusNo. of specimensSingle or paireda
ZIKV42Paired+4-fold increasePuerto Rico2016
DENV54Paired+4-fold increaseBrazil2009
WNV97SingleNDcHighest titerUnited States (South Dakota)2008
  • a Paired specimens, including acute specimens, were collected within 7 days of disease onset, and convalescent-phase specimens were collected within 7 to 30 days after onset of symptoms.

  • b A control serum panel consists of 30 non-DENV patient serum specimens, including IgG-positive yellow fever-17D (YF-17D) postvaccination sera (n = 10), acute-phase serum specimens from St. Louis encephalitis virus (SLEV; n = 2), chikungunya virus (n = 10), or other nonarboviral (n = 8) infections, and 46 normal human sera from the CDC blood bank.

  • c ND, not determined due to undetectable viremia.