Rotating PIS analysis of sensitivity and specificity of NAATs for detecting Chlamydia trachomatis in urine samples from mena

ComparisonNo. of samples testedNo. of C. trachomatis PIS-positive samples tested/total no.% sensitivity (95% CI)No. of C. trachomatis PIS-negative samples tested/total no.% specificity (95% CI)
AC2 vs PIS (Cobas, CTQ/GCQ, and m2000)1,187117/11998.3 (94.1–99.5)1,067/1,06899.9 (99.5–100.0)
CTQ/GCQ vs PIS (Cobas, AC2, and m2000)1,187116/11799.1 (95.3–99.8)1,069/1,07099.9 (99.5–100.0)
m2000 vs PIS (Cobas, AC2, and CTQ/GCQ)1,189118/11999.2 (95.4–99.9)1,069/1,07099.9 (99.5–100.0)
  • a AC2, Hologic Aptima Combo 2 CT/NG assay; Cobas, Cobas CT/NG test for use on the Cobas 6800/8800 systems; CTQ/GCQ, BD ProbeTec CT Qx and GC Qx amplified DNA assays; m2000, Abbot m2000 RealTime CT/NG assay; NAAT, nucleic acid amplification test; PIS, patient infected status.