TABLE 2

Clinical specimen stability results

Time pointStorage conditions (no. of days, temperature [°C], relative humidity [%])aLayer separation after 21 days (transport stability)bValid replicatesHIV-1 reactive rate (%)Mean log10 titerMean log10 titer difference from that at T0
1T0NA12/12c1003.450.00
221, 45, 85NA15/151003.42−0.03
321, 45, 85 + 28, 18–30No15/151003.480.03
21, 45, 85 + 28, 2–8No15/151003.38−0.07
21,45, 85 + 28, ≤10No14/141003.460.01
421, 45, 85 + 35, 18–30Yes14/141003.35−0.10
21, 45, 85 + 35, 2-8Yes15/151003.43−0.02
21, 45, 85 + 35, ≤10Yes15/151003.460.01
521, 45, 85 + 56, 18–30No15/151003.35−0.09
21, 45, 85 + 56, 2–8No15/151003.42−0.02
21, 45, 85 + 56, ≤10No15/151003.37−0.08
21, 45, 85 + 56, 18–30Yes14/141003.480.03
21, 45, 85 + 56, 2–8Yes15/151003.450.00
21, 45, 85 + 56, ≤10Yes15/151003.43−0.02
  • a T0, time of initial measurement.

  • b n/a, not applicable.

  • c Could not repeat as no additional T0 samples were available.