TABLE 1

Patient and control characteristics

CharacteristicValue(s)
CPA patients (n = 154)Healthy controls (n = 150)
No. (%) of females66 (42)60 (40)
Mean age (yrs)6452
Age range (yrs)32–8736–64
No. (%) with ImmunoCAP Aspergillus-specific IgG result:
    >40 mgA/liter (positive result)124 (81)
    ≤40 mgA/liter (negative result)a30 (19)
    >500 mgA/liter (high-positive result)11 (7)
    ≤40 mgA/liter (seronegative result)b10 (7)
No. (%) with Aspergillus fumigatus growth in sputum culture84 (55)
 A. fumigatus only55 (36)
 A. fumigatus + other Aspergillus spp.29 (19)
No. (%) with other Aspergillus (only) growth in sputum culture (A. niger [4], A. versicolor [1], A. montevidensis [1], A. insuetus [1], or A. terreus [1])8 (5)
No. (%) with COPDc52 (34)
No. (%) with prior tuberculosis23 (15)
No. (%) with ABPAd19 (12)
No. (%) with bronchiectasis31 (20)
No. (%) with nontuberculous mycobacterial infection13 (8)
No. (%) with diabetes17 (11)
No. (%) with sarcoidosis16 (10)
  • a Negative result for single serum sample tested.

  • b Negative results obtained consistently throughout patient history.

  • c COPD, chronic obstructive pulmonary disease.

  • d ABPA, allergic bronchopulmonary aspergillosis.