TABLE 2

Summary of results for LDBio Aspergillus ICT IgG-IgM test and routine serologya

Test% sensitivity (95% CI)% specificity
(95% CI)
(healthy controls
[n = 148])c
Youden's
index
(all sera
[n = 302])d
DOR
(95% CI)
(all sera
[n = 302])
All CPA
(n = 154)
High
positive
(n = 11)b
Seronegative
(n = 10)b
LDBio ICT91.6 (86.0, 95.4)100 (71.5, 100)90.0 (55.5, 99.8)98.0 (94.2, 99.6)0.896524 (146, 1,879)
ImmunoCAP80.5 (73.4, 86.5)100 (71.5, 100)0 (0, 30.9)NAeNANA
McNemar's (P value)0.007NA
  • a Results are reported against the cutoff of 40 mgA/liter recommended for use in United Kingdom laboratories at the time of publication.

  • b ImmunoCAP results were used to define the “high positive” and “seronegative” groups.

  • c Equivocal results (n = 2) were excluded from analysis.

  • d Youden's index = sensitivity + specificity − 1.

  • e NA, not applicable.