TABLE 3

Clinical performance comparison of four EUA molecular assays for the detection of SARS-CoV-2 in nasopharyngeal swab specimens (n = 104)

TABLE 3
  • a The reference standard was defined as the result obtained from at least 3 of the 4 molecular assays.

  • b Kappa values representing levels of agreement are categorized as follows: >0.90, almost perfect; 0.80 to 0.90, strong; 0.60 to 0.79, moderate; 0.40 to 0.59, weak; 0.21 to 0.39, minimal; (0 to 0.20), none.

  • c ± 95% CI, upper/lower 95% confidence interval.

  • d This one sample had cycle threshold (CT) values of 38.9 and 39.6 for N1 and N2, respectively, by the CDC assay.

  • e Cycle threshold (CT) value undetermined.

  • f These two samples had cycle threshold (CT) values of 36.2 and 38.5 by the Hologic assay.