Table 1

MICs of β-lactam and non-β-lactam antibiotics for the mecALGA251 MRSA isolates, determined by broth microdilution

Antimicrobial class and agentMIC range (μg/ml)
β-lactams
    Penicillins
        Penicillin0.4–8
        Oxacillin0.35–32
    Cephalosporins
        Cefoxitin>8–64
Non-β-lactams
    Glycopeptides
        Vancomycin0.5–1
        Teicoplanin0.5–1
    Lincosamides
        Clindamycin0.125–0.25
    Oxazolidinones
        Linezolid0.125–0.5
    Rifamycins
        Rifampin0.004–0.008
    Fosfomycins
        Fosfomycin1.2–9.6
    Folate pathway inhibitors
        Trimethoprim-sulfamethoxazole0.024–0.48
    Aminoglycosides
        Gentamicin0.2–0.4
        Tobramycin0.256–0.512
    Fluoroquinolones
        Ciprofloxacin0.08–0.16
        Levofloxacin0.2–0.4
        Moxifloxacin0.04–0.08
    Macrolides
        Erythromycin0.025–0.4
    Monoxycarbolic acids
        Mupirocin0.128–0.256
    Tetracyclines
        Tetracycline0.125–1
    Nitrofurans
        Nitrofurantoin>2–8
    Others
        Fusidic acid0.064–0.128