Table 2

Virulence microarray hybridization profiles of the mecALGA251 MRSA isolates assigned to spa CC843/CC1535 complex and spa types t978 and t5930

Gene classGene(s)DNA microarray hybridization profile of isolates assigned toa:
CC843/CC1535t978t5930
Species markerscoa, gapA, nuc, katA, spaPosPosPos
Hemolysinshla, hlb, hldPosPosPos
Immune evasionsak, chp, scnNegNegNeg
aurPosPosPos
splA, splBPosPosPos
splENeg/PosbPosPos
Superantigenstst1NegPosPos
sea, seb, see, sehNegNegNeg
sec-selNegPosPos
sed-sej-serNegNegNeg
seg-sei-sem-sen-seo-seuNegPosNeg
sek-seqNegNegNeg
Exfoliative toxinseta, etb, etdNegNegNeg
edinANegNegNeg
edinBPosNegNeg
Biofilmica operonPosPosPos
Capsulecap8cap5cap5
agr typeIIIIVI
  • a Only clinically relevant markers, including exotoxins and resistance genes, are shown. The table does not represent the complete hybridization profile of 334 probes on the array. Pos, positive; Neg, negative.

  • b Two t843 isolates and one t1773 isolate were splE positive.