Table 4

Comparative detection of coinfections by eSensor RVP and real-time PCR assaysa

Distinct combinations detected by real-time PCR assaysTotal no. of coinfectionsNo. of discrepant coinfectionsbDiscrepant analyteb or no. of discrepant analytes
Analyte 1Analyte 2Analyte 3Analyte 4
IV A H1IV B11IV B
IV A H1AdV10
IV A H3MPV10
IV A H3AdV21IV A H3
IV A (H1N1)pdm09RSV B10
IV BPIV type 321IV B
IV BAdV11AdV
RSV APIV type 310
RSV ARhV20
RSV AAdV21AdV
RSV BRhV71RSV B
PIV type 1RhV30
PIV type 1AdV10
PIV type 2RhV10
PIV type 2AdV10
PIV type 3MPV10
PIV type 3RhV10
MPVRhV31MPV
MPVAdV10
RhVAdV50
    Total dual infections3877/76c
IV A (H1N1)pdm09MPVRhV10
RSV ARhVAdV10
RSV BPIV type 1RhV10
RSV BRhVAdV10
PIV type 1RhVAdV11PIV type 1
PIV type 3MPVAdV10
MPVRhVAdV10
    Total triple infections711/21c
IV A (H1N1)pdm09PIV type 3MPVRhV10
    RSV APIV type 2RhVAdV10
    Total quadruple infections200/8c
Total coinfections4788/105c
  • a Abbreviations: IV, influenza virus; RSV, respiratory syncytial virus; PIV, parainfluenza virus; MPV, human metapneumovirus; RhV, rhinovirus; AdV, adenovirus.

  • b A discrepant coinfection or discrepant analyte was defined as one detected by real-time PCR but not detected by eSensor RVP.

  • c The denominator represents the expected number of viral detections.