Table 2

Sensitivity and specificity of two anti-Aspergillus antibody EIAs for the detection of Aspergillus-induced diseases

ParameterGroupa (no. of samples; no. of patients)EIAb
Bio-RadSerion
Sensitivity1a (51; 51)94.1–90.2%92.2–88.2%
1b (13; 13)92.3–92.3%84.6–76.9%
1a + 1b (64; 64)93.8–90.6%90.6–85.9%
Specificity2 (35; 26)54.3–60.0%60.0–71.4%
3 (50; 44)82.0–84.0%62.0–80.0%
4 (64; 49)67.2–75.0%42.2–54.7%
5 (222; 222)100.0–99.5%95.9–91.0%
2 + 3 + 4 + 5 (371; 341)87.3–89.6%75.7–84.4%
  • a Groups are defined in Materials and Methods.

  • b First and second percentages were obtained when equivocal results were considered as positives or negatives, respectively.