Table 3

Sensitivities and specificities of the two amplification systems

Material(s) and systemNo. of samples% Prevalence% Sensitivity95% CIdPositive LRNegative LR% Specificity
Biopsy specimen
    Amplicor47910.8671.1565–8937.200.2998.09
    TaqMan2887.2985.7164–9892.140.1499.07
Bronchial lavage fluid
    Amplicor3,0942.8160.9251–71198.390.3999.69
    TaqMan2,8371.8068.6356–81929.900.3199.93
Cavitary fluida
    Amplicor4221.4283.3354–113333.330.1799.75
    TaqMan1561.2850.00−19–1190.50100.00
Gastric aspirate
    Amplicor17412.6459.0938–8041.660.4198.58
    TaqMan10014.0042.8617–690.57100.00
CSFb
    Amplicor3621.3840.0017–10369.600.6099.43
    TaqMan2321.7225.00−17–670.75100.00
Pleural fluid
    Amplicor8661.9623.533–4465.020.7799.64
    TaqMan6621.669.09−7–260.91100.00
Pus
    Amplicor16415.3759.0940–7880.950.4199.27
    TaqMan8215.8576.9254–1000.23100.00
Sputum
    Amplicor1,4832.9990.7987–94216.620.0999.58
    TaqMan1,4038.9890.4885–960.10100.00
Urine
    Amplicor3682.9945.4516–750.55100.00
    TaqMan2701.48100.001000.00100.00
Other
    Amplicor3125.8187.5065–1100.13100.00
    TaqMan372.70100.001000.00100.00
Respiratoryc
    Amplicor4,7517.0981.0177–85215.940.1999.62
    TaqMan4,3404.4981.1576–871,638.050.1999.95
Nonrespiratory
    Amplicor2,6923.0160.3354–72102.610.4099.41
    TaqMan1,7273.2464.2950–75510.430.3699.87
Smear positive
    Amplicor27481.0298.6597–1004.440.0277.78
    TaqMan16384.05100.001000.00100.00
Smear negative
    Amplicor7,1693.2553.2247–60140.770.4799.62
    TaqMan5,9041.9049.1140–581,375.250.5199.96
All
    Amplicor7,4436.1575.5572–80167.360.2599.55
    TaqMan6,0674.0777.3372–821,087.420.2399.93
  • a Peritoneal and synovial.

  • b CSF, cerebrospinal fluid.

  • c Sputum, bronchial lavage fluid, and gastric aspirate.

  • d CI, confidence interval.