Table 6

MIC distributions for azole and echinocandin antifungal agents tested against isolates of uncommon species of Candida and Aspergillus, as well as non-Candida yeasts and non-Aspergillus molds identified by molecular methods (≥5 isolates per species) in SENTRY, 2010 to 2011

Species (no. tested)Antifungal agentaNo. at an MIC/MEC (μg/ml) of:
0.0070.0150.030.060.120.250.51248163264128
Candida species
    C. dubliniensis (50)ANF13171883
CSF22142381
MCF46231241
FLC161617
ITR110191442
PSC2728571
VRC41621
    C. fermentati (8)ANF44
CSF422
MCF161
FLC111311
ITR2411
PSC3311
VRC2231
    C. guilliermondii (19)ANF15841
CSF333442
MCF1154521
FLC1743211
ITR47251
PSC5545
VRC167311
    C. kefyr (16)ANF8422
CSF11311
MCF6721
FLC1582
ITR13732
PSC13732
VRC133
    C. lusitaniae (55)ANF1321819111
CSF141220135
MCF2237251051
FLC121311844111
ITR11131681141
PSC15101971111
VRC34126111
Non-Candida yeasts
    Cryptococcus neoformans (84)ANF84
CSF1173
MCF84
FLC3142426152
ITR8182422111
PSC14193016122
VRC41729295
    Rhodotorula mucilaginosa (5)ANF5
CSF23
MCF5
FLC5
ITR221
PSC221
VRC23
    Saccharomyces cerevisiae (6)ANF1122
CSF231
MCF51
FLC321
ITR222
PSC222
VRC321
    Trichosporon asahii (9)ANF9
CSF135
MCF9
FLC2511
ITR1152
PSC2331
VRC123111
    Trichosporon spp. (5)ANF5
CSF23
MCF5
FLC221
ITR1121
PSC2111
VRC32
Aspergillus species
    A. flavus SC (19)ANF1612
CSF496
MCF1522
ITR127
PSC3151
VRC1171
    A. niger SC (15)ANF1032
CSF5811
MCF1212
ITR86
PSC95
VRC841
    A. terreus SC (7)ANF3211
CSF331
MCF511
ITR133
PSC43
VRC16
Non-Aspergillus molds
    Gibberella fujikuroi SC (6)ANF15
CSF6
MCF6
ITR15
PSC12111
VRC11211
  • a ANF, anidulafungin; MCF, micafungin; CSF, caspofungin; ITR, itraconazole; PSC, posaconazole; VRC, voriconazole.