Table 3

MIC/MEC distributions for isavuconazole and six comparator antifungal agents tested against Aspergillus spp. using CLSI broth microdilution methods

Species (n)Antifungal agentaNo. of isolates with an MIC/MEC (μg/ml) of:
≤0.0080.0150.030.060.120.250.5124≥8
A. fumigatus (71)ISA648161
ITR7631
PSC221408
VRC20465
ANF1948121
CSF44423
MCF1039211
A. niger (11)ISA821
ITR65
PSC56
VRC542
ANF632
CSF344
MCF533
A. flavus (10)ISA181
ITR10
PSC351
VRC37
ANF613
CSF64
MCF442
A. terreus SC (6)bISA132
ITR24
PSC33
VRC51
ANF321
CSF411
MCF411
A. sydowii (3)ISA111
ITR12
PSC12
VRC21
ANF111
CSF12
MCF12
  • a ISA, isavuconazole; ITR, itraconazole; PSC, posaconazole; VRC, voriconazole; ANF, anidulafungin; CSF, caspofungin; MCF, micafungin.

  • b SC, species complex.