TABLE 1

Characteristics of 180 subjects with OAI and NIOa

DemographicsbSubjects with OAI (n = 125)Subjects with NIO (n = 55)P valuec
Male sex (no. [%])78 (62.4)27 (49.0)0.09
Age (median [range]) (yr)41 (21–60)37 (12–62)0.002
Age of implants (median [range]) (mo)20.9 (0–53.0)30.21 (1.4–60.18)0.006
Clinical characteristics (no. [%])
    Diabetes mellitus17 (9)1 (1)0.012
    Coronary diseases5 (3)3 (2)0.708
    Liver cirrhosis0 (0)1 (1)0.315
    Solid malignancy3 (2)3 (2)0.381
    Corticosteroids4 (2)0 (0)0.309
    Rheumatoid arthritis4 (2)0 (0)0.309
    Alcohol abuse11 (6)0 (0)0.018
    Smoking30 (17)3 (2)0.02
No. (%) of revisions (>1)22 (12)3 (2)0.023
No. (median range) of peri-implant tissue samples taken2.9 (2–12)2.64 (2–8)0.54
Prior use of antimicrobials (no. [%])d39 (31.2)1 (1.81)<0.001
  • a OAI, osteosynthesis-associated infection; NIO, noninfected osteosynthesis.

  • b All percentages are in relation to the number of subjects with OAI or NIO, unless otherwise indicated.

  • c The patient characteristics were summarized as frequencies and percentages or median values and compared using the Pearson chi-square test or Fisher's exact test, as appropriate, with nominal variables and the Mann-Whitney test or t test, as appropriate, with continuous variables (SPSS version 19.0). All tests were two sided, and P values of <0.05 were considered statistically significant.

  • d Patient who received a minimum of 1 day of antibiotic therapy within 14 days prior to the removal of the implants.