TABLE 1

Characteristics of patients with serum HCV RNA levels that were undetectable by CAP/CTMa

Patient characteristicPatient 1Patient 2Patient 3Patient 4
Age (yr)49545456
GenderMaleMaleMaleMale
Liver histology (fibrosis/activity)d4/34/24/1Not done
Alanine aminotransferase (IU/liter)124296251
Platelet count (per mm3)89,00055,000134,000110,000
Anti-HCV antibody (COI)b66.355.871.853.6
HCV RNA with ARTc (log IU/ml)5.95.65.95.6
HCV core antigen (fmol/liter)1,3403,3206231,586
HCV genotype2a2a2a2a
  • a CAP/CTM, Roche AmpliPrep/Cobas TaqMan HCV assay.

  • b HCV, hepatitis C virus; COI, cutoff index.

  • c ART, Abbott RealTime HCV assay.

  • d Liver histology according to the criteria of Desmet et al. (8).