TABLE 4

Clinical, genetic, and phenotypic information of sequence types represented by more than one K. oxytoca isolate

Sequence typeIsolateToxinaGeographic originbIsolation siteDiagnosiscIsolation date (mo/yr)Antibiotic resistance typedNosocomial (N)/outpatient (O)eClonal complexCluster
134+AUT (Graz)StoolAAHC3/2004OA
145+AUT (Graz)StoolFollow-up/AAHC4/2004OA
256+AUT (Graz)StoolAAHC4/2004O2A
2379+ESPStool/rectal swabNA5/2009CREN2A
433AUT (Styria)SkinCSSTI5/2004O8A
473AUT (Graz)StoolAsymptomatic carrier4/2004ESBLN8A
481+AUT (Graz)StoolAsymptomatic carrier6/2005O8A
4204+AUT (Graz)StoolAAHC8/2008ESBLO8A
4231AUT (Graz)Respiratory tractNosocomial pneumonia10/2010ESBL + CREN8A
4402AUT (Graz)Respiratory tractPneumonia6/2013O8A
937+AUT (Graz)StoolAsymptomatic carrier4/2004ESBLNA
9128+AUT (Styria)StoolIBD3/2007OA
9188+AUT (Vienna)StoolAAHC1/2008NAA
9222+AUT (Graz)StoolAAHC11/2009ESBLOA
9232+AUT (Graz)BloodAAHC with bacteremia8/2010OA
9382+AUT (Graz)StoolIBD8/2013OA
9425+GERStoolDiarrhea2013OA
1175AUT (Graz)skinDFS4/2004O4B1
11400AUT (Graz)Respiratory tractVAP6/2013N4B1
18113AUT (Burgenland)StoolAsymptomatic carrier6/2005O2A
18336+HKGStoolDiarrheaNANA2A
33180AUT (Graz)StoolAAHC12/2007O1A
33227+AUT (Vienna)StoolAAHC6/2010O1A
36195+AUT (Graz)StoolUTI1/2008NA
36195-HAUT (Graz)Urinary tractUTI1/2008NA
38131AUT (Styria)StoolAsymptomatic carrier4/2007OB2
38333+AUT (Salzburg)StoolColitis3/2014OB2
4021AUT (Graz)Respiratory tractVAP11/2003NB1
40284AUT (Graz)Respiratory tractNosocomial pneumonia2/2012NB1
4123AUT (Graz)Respiratory tractVAP11/2003N3B1
41389AUT (Graz)Respiratory tractPneumothorax9/2013O3B1
4440AUT (Graz)Respiratory tractVAP5/2004ESBLNB1
44179AUT (Styria)Urinary tractUTI11/2007ESBLOB1
  • a Cytotoxicity was assessed via an MTT-based cell culture assay (6).

  • b AUT, Austria; ESP, Spain; GER, Germany; HKG, Hong Kong.

  • c AAHC, antibiotic-associated hemorrhagic colitis; NA, information not available; CSSTI, complicated skin and skin structure infection; IBD, inflammatory bowel disease; DFS, diabetic foot syndrome; VAP, ventilator-associated pneumonia; UTI, urinary tract infection.

  • d All isolates were resistant to ampicillin. ESBL, extended spectrum β-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.

  • e Isolates were classified as nosocomial when infection occurred after 48 h of hospitalization.