Bacteriology, management, and outcomes among combat-injured U.S. service members (2009-2011)

CharacteristicaResults for:P value 1cP value 2d
IFIb case wounds (n = 82)Non-IFI wounds
With SSTIs (n = 63)Without SSTIs (n = 73)
SSTI (no. [%])
    Bacteria identified during infection workup52 (63)34 (54)NAe0.194NA
    MDROs identified during infection workup25 (30)17 (27)NA0.416NA
    Recurrent SSTI at same anatomic site9 (11)6 (10)NA0.738NA
Time from injury to wound closure (median days [IQR])f16 (11−22)12 (9–18)9 (6–13)0.008<0.001
OR visits at LRMC and U.S. MTFs (median [IQR])9 (6–12)7 (5–10)6 (5–7)0.0100.002
Type of initial wound closure (no. [%])g0.8830.828
    STSG + FTSG + Integra29 (35)18 (29)17 (23)
    DPC48 (59)36 (57)46 (63)
    Rotational flap1 (1)00
    Free flap2 (2)2 (3)2 (3)
Surgical amputations/revisions (no. [%])h63 (77)45 (71)26 (36)0.460<0.001
  • a DPC, delayed primary closure; FTSG, full-thickness skin graft; IQR, interquartile range; LRMC, Landstuhl Regional Medical Center; MDRO, multidrug-resistant organism; MTF, military treatment facility; OR, operating room; STSG, split-thickness skin graft.

  • b IFI, invasive fungal wound infection.

  • c P value 1: compares IFI case wounds and non-IFI wounds with SSTIs.

  • d P value 2: compares non-IFI wounds with and without SSTIs.

  • e NA, not applicable.

  • f Two non-IFI wounds with SSTIs were missing the time to wound closure data.

  • g Two fungus-infected wounds, 7 non-IFI wounds with SSTIs, and 8 non-IFI wounds without SSTIs were missing type of closure data.

  • h Operative procedures occurred at the U.S. MTFs.