TABLE 3

Microbiological findings by wound typea

Microbiological characteristicResults for:
IFIb case woundsNon-IFI woundsc
With SSTIsdWithout SSTIs
Total wounds (no. [%])826373
Days from injury to first culture with mold growth (median [IQRe])f6 (3−9)4 (3−8)2 (2−2)
Growth of molds (no. [%])
    Mucoralesg29 (35)1 (2)1 (1)
        Mucor spp.15 (18)1 (2)0
        Saksenaea vasiformis5 (6)00
        Rhizopus spp.1 (1)00
    Aspergillusg24 (29)3 (5)1 (1)
        A. terreus8 (10)1 (2)0
        A. flavus7 (9)00
        A. niger2 (2)00
        A. fumigatus1 (1)00
    Fusarium17 (21)00
    Other molds27 (33)6 (10)1 (1)
    More than 1 mold22 (27)1 (2)0
Days from injury to first culture with bacterial growth (median [IQR])h6 (3−9)8 (5−17)15 (7−24)
Growth of bacteria/yeast (no [%])
    Candida spp.11 (13)5 (8)0
    Staphylococcus aureusi3 (4)5 (8)1 (1)
        Methicillin-resistant S. aureus2 (2)4 (6)0
    Coagulase-negative Staphylococcus13 (16)9 (14)6 (8)
    Enterococcus spp.37 (45)22 (35)0
        Vancomycin-resistant enterococci2 (2)1 (2)0
    Escherichia coli19 (23)17 (27)1 (1)
    Klebsiella spp.2 (2)2 (3)0
    Pseudomonas aeruginosa16 (20)12 (19)2 (3)
    Acinetobacter spp.16 (20)18 (29)2 (3)
    Other Gram-negative rods13 (16)7 (11)1 (1)
    Multidrug-resistant Gram-negative rods29 (35)26 (41)4 (6)
  • a Wounds may have growth of more than one type of organism so the sum may be >100%.

  • b IFI, invasive fungal wound infection.

  • c Non-IFI wounds may have growth of mold without meeting the clinical requirement to be classified as an IFI case wound (i.e., recurrent wound necrosis); therefore, these wounds are considered to be colonized with mold.

  • d SSTI, skin and soft tissue infections.

  • e IQR, interquartile range.

  • f P = 0.782 for IFI wounds versus non-IFI wounds with SSTIs.

  • g Wounds also grew mold that was not otherwise specified.

  • h P = 0.003 for IFI wounds versus non-IFI wounds with SSTIs.

  • i Includes both methicillin-resistant and methicillin-susceptible.