Detection of uropathogens in UTI cohort without symptom improvementa

Postenrollment questionnaire response (sample identifier)Antibiotic prescribedUropathogen(s) detected by protocol(s):
Standard urine culture and expanded-spectrum EQUCExpanded-spectrum EQUC onlyd
Same (145)SMZ-TMPbEscherichia coliStreptococcus anginosus
Same (048)NitrofurantoinEscherichia coliStreptococcus anginosus
Same (134)SMZ-TMPEscherichia coliAerococcus urinae, Corynebacterium riegelii
Same (033)CiprofloxacinKlebsiella pneumoniae
Same (060)NitrofurantoinEscherichia coli
Same (109)NitrofurantoinEscherichia coli
Same (122)CiprofloxacinEscherichia coli
Same (135)NitrofurantoinEscherichia coli
Same (136)NitrofurantoinEscherichia coli
Worse (082)NitrofurantoinEscherichia coli
Same (140)Staphylococcus lugdunensis
Same (116)Escherichia coli
Worse (128)Escherichia coli
Same (126)Lactobacillus speciescStaphylococcus lugdunensis, Streptococcus anginosus
Same (121)Proteus mirabilis
Same (029)Aerococcus urinae, Klebsiella pneumoniae
Same (139)Alloscardovia omnicolens, Oligella urethralis, Morganella morganii
Same (052)Streptococcus anginosus
Same (067)Streptococcus anginosus
Worse (025)Candida albicans
Worse (112)Streptococcus agalactiae, Streptococcus anginosus
Worse (142)Escherichia coli
Same (084)
Same (108)
  • a Uropathogens detected and missed by the standard urine culture in urine samples obtained by catheter from the UTI cohort patients who reported feeling the same or worse for the postenrollment questionnaire. Antibiotics were prescribed based on the reporting of the standard urine culture results.

  • b SMZ-TMP, sulfamethoxazole-trimethoprim.

  • c Lactobacillus species is not considered a uropathogen, but it was detected at >100,000 CFU/ml by standard urine culture.

  • d All of the uropathogens detected by the expanded-spectrum EQUC protocol would have been detected using the streamlined EQUC protocol.