TABLE 1

Comparison of Xpert HPV test results using paired vaginal and cervical specimens

Virus and vaginal specimen typeNo. of cervical specimensPPA (%) (95% CI), NPA (%) (95% CI), OPA (%) (95% CI), kappa value (95% CI)
PositiveNegativeTotal
HPV-1694.3 (92.8, 95.8), 99.6 (99.2, 100.0), 99.4 (98.9, 99.9), 0.91 (0.86, 0.97)
    Positive33437
    Negative2966968
    Total359701,005
HPV-18/4581.3 (78.8, 83.8), 98.8 (98.1, 99.5), 98.5 (97.7, 99.3), 0.63 (0.48, 0.77)
    Positive131225
    Negative3977980
    Total169891,005
Other hrHPVs91.1 (89.3, 92.9), 94.8 (93.4, 96.2), 94.4 (92.9, 95.9), 0.72 (0.65, 0.79)
    Positive8248130
    Negative8867875
    Total909151,005
All hrHPVs90.3 (88.4, 92.2), 93.9 (92.4, 95.4), 93.4 (91.8, 95.0), 0.74 (0.70, 0.79)
    Positive11254166
    Negative12827839
    Total1248811,005