TABLE 3

Results of positive respiratory virus tests over two consecutive influenza seasons

CharacteristicNo. (%) in season:
1 (n = 198)2 (n = 139)
Positive test result
    Rapid antigen (alone)51 (26)
    Prodesse (alone)56 (28)
    Rapid antigen with reflex to Prodessea78 (39)
        Discordant (rapid antigen negative, Prodesse positive)64
        Concordant (rapid antigen positive, Prodesse positive)14
    Luminex13 (7)
    Full-panel FilmArray131 (94)
    Individual orders for influenza virus or RSV FilmArray8 (6)
Viruses detected
    Influenza A virus142 (72)b36 (26)c
    Influenza B virus16 (8)18 (13)
    RSV29 (15)9 (6)
    Human metapneumovirus3 (2)27 (19)
    Rhinovirus/enterovirus8 (4)42 (30)
    Adenovirus1 (0.5)1 (0.7)
    Coronavirus NL63NAd4 (3)
    Coronavirus HKU1NA2 (1)
    Parainfluenza virus 100
    Parainfluenza virus 201 (0.7)
    Parainfluenza virus 303 (2)
    Parainfluenza virus 4NA1 (0.7)
Viral coinfection
    Double1 (0.5)e3 (2)f
    Triple01 (0.7)g
  • a No patients had a positive rapid antigen test followed by a negative Prodesse PCR. Of the 78 patients who were tested by both the rapid antigen and Prodesse tests, 73 were positive for influenza virus (60 were discordant, and 13 concordant) and 5 were positive for RSV (4 were discordant and 1 was concordant).

  • b One hundred forty-one patients tested positive for influenza A virus with the subtype not specified; one tested positive for influenza A virus H3.

  • c Twenty-one patients tested positive for influenza A virus H3, 14 tested positive for influenza A virus H1 2009, and 1 tested positive for influenza A virus with the subtype not specified.

  • d NA, not applicable.

  • e Double coinfection with human metapneumovirus and rhinovirus.

  • f Double coinfections with rhinovirus/enterovirus and parainfluenza virus 3, rhinovirus/enterovirus and human metapneumovirus, and human metapneumovirus and parainfluenza virus 2.

  • g Triple coinfection with influenza A virus H1 2009, rhinovirus/enterovirus, and coronavirus NL63.