TABLE 5

Univariate and multivariate linear regressions for outcomes using FilmArray PCR compared to conventional testinga

OutcomePatients positive for influenza virus (n = 212)Patients positive for non-influenza viruses (n = 125)
Unadjusted coefficient (95% CI)P valueAdjusted coefficient (95% CI)P valueUnadjusted coefficient (95% CI)P valueAdjusted Coefficient (95% CI)P value
Length of stay−0.12 (−0.62, 0.37)0.63−0.37 (−0.73, −0.018)0.040−0.57 (−1.11, −0.016)0.044−0.091 (−0.52, 0.34)0.68
Duration of antimicrobial useb−0.61 (−1.28, 0.061)0.074−0.68 (−1.29, −0.060)0.032−0.091 (−0.69, 0.51)0.760.12 (−0.43, 0.67)0.66
No. of chest radiographsc−0.43 (−0.80, −0.067)0.020−0.42 (−0.72, −0.13)0.005−0.32 (−0.78, 0.13)0.160.022 (−0.33, 0.38)0.90
Time to anti-influenza treatmentd−0.18 (−0.69, −0.33)0.48−0.20 (−0.65, 0.25)0.37NAe
  • a All outcomes in multivariate analyses were adjusted for age, immunosuppressed status, asthma, and admission to ICU. Length of stay, duration of antimicrobial use, and time to anti-influenza treatment were analyzed using the natural log of data due to nonnormal distributions. The number of chest radiographs was analyzed using negative binomial regression.

  • b Patients positive for influenza virus who received antimicrobials, n = 96 of 119 due to logarithmic transformation (only values above 0 could be transformed). Patients positive for non-influenza viruses who received antimicrobials, n = 84 of 94 due to logarithmic transformation.

  • c Patients positive for influenza virus who had a chest radiograph, n = 188. Patients positive for non-influenza viruses who had a chest radiograph, n = 113.

  • d Patients who received anti-influenza treatment, n = 123 of 129 due to logarithmic transformation.

  • e NA, not applicable.