TABLE 3

M. genitalium macrolide antibiotic resistance marker frequency in female and male subjects

CategoryNo. with 23S rRNA 2058/2059a mutation/total no. (% [95% CI])
FemaleMale
All subjects65/128 (50.8 [42.2–59.3])21/50 (42 [29.4–55.8])
Race/ethnicity
    Black59/102 (57.8 [48.1–67])b20/44 (45.4 [31.7–60])
    White5/22 (22.7 [10.1–43.4])1/4 (25 [4.6–70])
    Unknown race1/4 (25 [4.6–70])0/2 (0 [0–65.8])
    Hispanic1/6 (16.7 [30.1–56.4])1/2 (50 [9.5–90.6])
    Non-Hispanic61/112 (54.5 [45.2–63.4])18/43 (41.8 [28.4–56.7])
    Unknown ethnicity3/10 (30 [10.8–60.3])2/5 (40 [11.8–76.9])
Symptomatic status
    Symptomatic57/102 (55.9 [46.2–65.1])c9/21 (42.9 [24.5–63.5])
    Asymptomatic8/26 (30.8 [16.5–50])12/29 (41.4 [25.5–59.3])
Age
    14–24 yr52/97 (53.6 [43.7–63.2])12/24 (50 [31.4–68.6])
    25–47 yr13/31 (41.9 [26.4–59.2])9/26 (34.6 [19.4–53.8])
  • a E. coli 23S rRNA numbering.

  • b OR of 2.54 (P = 0.0734) versus white females.

  • c OR of 1.81 (P = 0.172) versus asymptomatic females.