TABLE 2.

Effect of adding radiolabeled precursors early on in vitro drug sensitivity tests

Time (h) of contactTime (h) of freezingGeometric mean IC50 in nM (95% CI)a
T3/SAR97276AS
HXEthanolamineHXEthanolamine
0-4848285.5 (151.9-536.9)38.5 (14.3-103.5)1.7 (1.3-2.2)1.7 (1.2-2.4)
24-484823.1 (15.5-34.4)22.3 (12.8-38.7)1.3 (1.2-1.5)0.9 (0.2-6)
48-66664.6 (4-5.2)9.4 (8.7-10.3)1.1 (0.8-1.4)1.5 (1.4-1.7)
  • a HX, hypoxanthine.