TABLE 2.

Estimates of SDA, PCR, TMA, and culture sensitivities and specificities for detection of N. gonorrhoeae or C. trachomatis by reference standard

StandardTestNo. infected% Sensitivity (95% CI)No. uninfected% Specificity (95% CI)
For N. gonorrhoeae
    Infected if any two of three comparator tests are positive; otherwise, uninfectedSDA3497.1 (84.7-99.9)34198.8 (97.0-99.7)
PCR3591.4 (76.9-98.2)34098.5 (96.6-99.5)
TMA33100.0 (89.4-100.0)34298.3 (96.2-99.4)
Culture3666.7 (49.0-81.4)339100.0 (98.9-100.0)
    Infected if all three comparator tests are positive; otherwise, uninfectedSDA23100.0 (85.2-100.0)35296.0 (93.4-97.8)
PCR2495.8 (78.9-99.9)35196.0 (93.4-97.8)
TMA23100.0 (85.2-100.0)35295.5 (92.7-97.4)
Culture3271.9 (53.3-86.3)34399.7 (98.4-100.0)
For C. trachomatis
    Infected if any two of three comparator tests are positive; otherwise, uninfectedSDA5192.2 (81.1-97.8)33696.4 (93.8-98.1)
PCR5780.7 (68.1-90.0)33098.5 (96.5-99.5)
TMA47100.0 (92.5-100.0)34095.6 (92.8-97.5)
Culture6136.1 (24.2-49.4)32699.7 (98.3-100.0)
    Infected if all three comparator tests are positive; otherwise, uninfectedSDA21100.0 (83.9-100.0)36689.6 (86.0-92.6)
PCR2295.5 (77.2-99.9)36591.8 (88.5-94.4)
TMA21100.0 (83.9-100)36688.8 (85.1-91.8)
Culture4645.7 (30.9-61.0)34199.4 (97.9-99.9)