TABLE 1.

Molecular analysis, residue positions, and comparison of amino acid sequences of different gene products of swine pandemic (H1N1) 2009 influenza virus isolates with selected H1N1 virusesa

StrainHA geneNA genePB2PB1-F2eM 31NS 92
Cleavage siteRBS
187 (190)222 (225)223 (226)Stalk deletion275590591627701
BM/1/18SIQSR/GLFDDQNoHGQKDYesSD
Sw/KR/CAN01/04SIQSR/GLFDGQNoHSREDYesSD
CA/04/09SIQSR/GLFDDQNoHSREDNoND
SG/GP2711/09SIQSR/GLFDDQNoHSREDNoND
Sw/AB/OTH33-8/09SIQSR/GLFDDQNoHSREDNoND
Sw/SG-Q/M168/09SIQSR/GLFDDQNoHSREDNoND
Tk/CL/6504-3/09SIQSR/GLFDDQNoHSREDNoND
KR/CJ01/09SIQSR/GLFDDQNoHSREDNoND
KR/CJ19/09SIQSR/GLFDDQNoHSREDNoND
KR/CJ24/09SIQSR/GLFDDQNoHSREDNoND
KR/CJ63/09SIQSR/GLFDDQNoHSREDNoND
KR/CJ112/09SIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ01/09bSIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ07/09bSIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ09/09cSIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ10/09cSIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ24/09dSIQSR/GLFDDQNoHSREDNoND
Sw/KR/SCJ33/10dSIQSR/GLFDDQNoHSREDNoND
  • a Molecular marker(s) previously identified to impact replication, pathogenesis, or drug resistance in respective segments are indicated. Numbers are position of residue, with H3 numbering in parentheses. AB, Alberta; BM, Brevig Mission; CA, California; CL, Chile; KR, Korea; SG, Singapore; RBS, receptor binding site; Sw, swine; Tk, turkey.

  • b Group I swine isolates.

  • c Group II swine isolates.

  • d Group III swine isolates.

  • e Expression of the PB1-F2 protein.