TABLE 1.

Susceptibility of 30 KPC-producing E. coli isolates to β-lactams

IsolateRibotypeMIC (μg/ml)a
Broth microdilution methodEtest method
IPMMERDORETPIPMMERDORETPCAZTZB
Brooklyn isolates
    DM133A411160.7511.58>256
    KB86A40.51140.51.50.7524>256
    KB801A4428422812192
    ME57B41146131.5896
    ME236A40.51230.520.524256
    LU60C24216822648>256
    MA82A8164321261224>256>256
    MA46D822412336256>256
    ME366C220.5410.7521.53224
Queens isolates
    E1A411240.754112>256
    E2E8168321212>32>32>256>256
    E3F42248343>256>256
    E4G18483481212896
    E5H42421236312>256
    E6A4218632848>256
    E7I88216884>323264
    E10A41124141.512>256
    E11A282888368>256
    E12I32328>32>32328>32>256>256
    E13J4418833424256
    E14K822212462192>256
    E16I444168488>256>256
    E18A440.58348624>256
    E19A888161661616128>256
Connecticut isolates
    F5483A20.250.5120.380.50.58>256
    H1788A20.50.50.520.380.50.5424
    J0597A20.50.5120.50.380.75648
    N3201A412130.380.381.5448
    T9322A411230.750.521296
    W3490A20.2510.520.750.750.5432
  • a IPM, imipenem; MER, meropenem; DOR, doripenem; ETP, ertapenem; CAZ, ceftazidime; TZB, piperacillin-tazobactam.