TABLE 1

Accuracy of Vitek MS v3.0 compared to sequencing for clinical isolates included in the database

Reference identificationNo. (%) with indicated Vitek MS identification
Correct to species levelCorrect to genus levelIncorrect resultsNo identification
Mucorales (n = 118)
    Mucor racemosus complex (n = 30)24 (80)6 (20)
    Rhizopus arrhizus complex (n = 28)22 (79)6 (21)
    Rhizopus microsporus complex (n = 29)26 (90)1 (3)2 (7)
    Lichtheimia corymbifera (n = 31)29 (94)2 (6)
    Total101 (86)1 (<1)16 (14)
Dimorphs (n = 141)
    Blastomyces dermatitidis (n = 40)40 (100)
    Coccidioides immitis/posadasii (n = 38)38 (100)
    Histoplasma capsulatum (n = 32)32 (100)
    Sporothrix schenckii complex (n = 31)31 (100)
    Total141 (100)
Dermatophytes (n = 291)
    Arthroderma benhamiaea (n = 1)1 (100)
    Microsporum audouinii (n = 33)30 (91)1 (3)2 (6)
    Microsporum canis (n = 31)30 (97)1 (3)
    Microsporum gypseum (n = 35)32 (91)3 (9)
    Epidermophyton floccosum (n = 31)30 (97)1b (3)
    Trichophyton mentagrophytes complexa (n = 1)1 (100)
    Trichophyton interdigitale (n = 30)29 (97)1 (3)
    Trichophyton rubrum (n = 31)31 (100)
    Trichophyton tonsurans (n = 33)30 (91)1 (3)2 (6)
    Trichophyton verrucosum (n = 31)18 (58)9 (29)4 (13)
    Trichophyton violaceum (n = 34)14 (41)14 (41)6 (18)
    Total246 (85)26 (9)12 (4)7 (2)
Dematiaceous (n = 325)
    Alternaria alternata (n = 32)30 (94)2 (6)
    Curvularia hawaiiensis (n = 26)25 (96)1 (4)
    Curvularia spicifera (n = 35)34 (97)1b (3)
    Exserohilum rostratum (n = 35)19 (54)16c (46)
    Exophiala dermatitidis (n = 31)31 (100)
    Exophiala xenobiotica (n = 32)25 (78)7 (22)
    Scedosporium boydii (n = 32)30 (94)1 (3)1 (3)
    Scedosporium apiospermum (n = 41)41 (100)
    Scedosporium prolificans (n = 32)32 (100)
    Cladophialophora bantiana (n = 29)28 (97)1 (3)
    Total295 (91)2 (<1)28 (9)
Aspergillus species (n = 328)
    Aspergillus brasiliensis (n = 31)29 (94)2 (7)
    Aspergillus calidoustus (n = 33)29 (88)4 (12)
    Aspergillus flavus/oryzae (n = 33)33 (100)
    Aspergillus fumigatus (n = 32)32 (100)
    Aspergillus lentulus (n = 30)30 (100)
    Aspergillus nidulans (n = 33)32 (97)1 (3)
    Aspergillus niger complex (n = 37)32 (87)5 (14)
    Aspergillus sydowii (n = 30)30 (97)1 (3)
    Aspergillus terreus complex (n = 34)32 (94)2 (6)
    Aspergillus unguisa (4)4 (100)
    Aspergillus versicolor (n = 31)22 (71)1 (3)8 (26)
    Total305 (93)1 (<1)23 (7)
Other potential pathogens (n = 316)
    Fusarium oxysporum complex (n = 31)30 (97)1 (3)
    Fusarium proliferatum (n = 30)30 (100)
    Fusarium solani complex (n = 39)33 (85)6 (15)
    Paecilomyces variotii (n = 30)30 (100)
    Penicillium chrysogenum (n = 30)30 (100)
    Penicillium citrinuma (n = 1)1 (100)
    Rasamsonia argillacea (n = 34)29 (85)5 (15)
    Acremonium sclerotigenum (n = 30)30 (100)
    Lecythophora hoffmannii (n = 30)27 (90)3 (10)
    Sarocladium kiliense (n = 30)30 (100)
    Purpureocillium lilacinum (n = 31)29 (94)2 (6)
    Total299 (95)17 (5)
Total molds (n = 1,519)1,387 (91)27 (2)15 (1)91 (6)
  • a Not included in FDA claim.

  • b No identification due to spectra of insufficient quality on all repeat testing.

  • c For 5 of 16 isolates, no identification due to spectra of insufficient quality on all repeat testing.