TABLE 4

Results for all clinical prospective and retrospective samplesa

TargetNo. of TP/no. of TP + FNPPA (%) (95% CI)No. of TN/no. of TN + FPNPA (%) (95% CI)OPA (%) (95% CI)
Adenovirus109/11793.2 (87.1–96.5)2,759/2,79198.9 (98.4–99.2)98.6 (98.1–99.0)
Coronavirus217/25585.1 (80.2–88.9)2,638/2,65299.5 (99.1–99.7)98.2 (97.7–98.6)
Human metapneumovirus112/12093.3 (87.4–96.6)2,782/2,78899.8 (99.5–99.9)99.5 (99.2–99.7)
Human rhinovirus/enterovirus530/56094.6 (92.5–96.2)2,244/2,34595.7 (94.8–96.4)95.5 (94.7–96.2)
Influenza A virusb181/19393.8 (89.4–96.4)2,710/2,71499.9 (99.6–99.9)99.4 (99.1–99.7)
Influenza A H1 virus0/02,908/2,908100 (99.9–100)100 (99.9–100)
Influenza A 2009 H1N1 virus97/10295.1 (89.0–97.9)2,800/2,80699.8 (99.5–99.9)99.6 (99.3–99.8)
Influenza A H3 virus79/8889.8 (81.7–94.5)2,819/2,819100 (99.9–100)99.7 (99.4–99.8)
Influenza B virus60/6789.6 (80.0–94.8)2,836/2,84199.8 (99.6–99.9)99.6 (99.3–99.8)
Parainfluenza virus 167/7391.8 (83.2–96.2)2,832/2,83499.9 (99.7–100)99.7 (99.5–99.9)
Parainfluenza virus 267/7391.8 (83.2–96.2)2,833/2,83599.9 (99.7–100)99.7 (99.5–99.9)
Parainfluenza virus 3101/11191.0 (84.2–95.0)2,792/2,79799.8 (99.6–99.9)99.5 (99.2–99.7)
Parainfluenza virus 426/2892.9 (77.4–98.0)2,873/2,88099.8 (99.5–99.9)99.7 (99.4–99.8)
Respiratory syncytial virus subtype A60/6789.6 (80.0–94.8)2,832/2,833100 (99.8–100)99.7 (99.5–99.9)
Respiratory syncytial virus subtype B111/11894.1 (88.3–97.1)2,780/2,78299.9 (99.7–100)99.7 (99.4–99.8)
Chlamydia pneumoniae3/650.0 (18.8–81.2)2,901/2,902100 (99.8–100)99.9 (99.6–99.9)
Mycoplasma pneumoniae14/1593.3 (70.2–98.8)2,891/2,89399.9 (99.7–100)99.9 (99.7–100)
  • a FP, false-positive result; FN, false-negative result; TP, true-positive result; TN, true-negative result. PPA, positive percent agreement; NPA, negative percent agreement; OPA, overall percent agreement (defined in comparison to the comparator method); CI, confidence interval.

  • b Influenza A virus comparator results detected 102 samples with A 2009 H1, 88 with A H3, and 3 with no subtype.