TABLE 1

Xpert TV versus InPouch, Aptima, and PIS results for female subjectsa

Sample typeReference test or patient statusTotal no. testedSensitivity95% CISpecificity95% CI% prevalencePPV (%)NPV (%)
ESInPouch1,79998.7 (153/155)95.4–99.897.6 (1,604/1,644)96.7–98.38.689.399.9
Aptima1,799100 (175/175)98.3–99.398.9 (1,606/1,624)98.3–99.39.790.7100
PIS1,79998.9 (175/177)96.0–99.998.9 (1,604/1,622)98.3–99.39.890.799.9
PC-VSInPouch1,79196.9 (156/161)92.9–99.097.7 (1,593/1,630)96.9–98.49.080.8.99.7
Aptima1,79197.4 (186/191)94.0–99.199.6 (1,593/1,600)99.1–99810.796.499.7
PIS1,79196.4 (186/193)92.7–98.599.6 (1,591/1,598)99.1–99.810.896.499.6
URInPouch1,79397.7 (148/150)95.3–99.897.7 (1,606/1,643)96.9–98.48.480.099.9
Aptima1,79399.4 (178/179)96.9–10099.6 (1,607/1,614)99.1–99.810.096.299.9
PIS1,79398.4 (180/183)95.3–99.799.7 (1,605/1,610)99.3–99.910.297.399.8
  • a Values in parentheses are the number of true positives over the total of true positives plus false negatives (sensitivity) and the number of true negatives over the total of true negatives plus false positives (specificity). PIS, patient infected status (see Materials and Methods); PPV, positive predictive value; NPV, negative predictive value; ES, endocervical swab; PC-VS, patient-collected vaginal swab; UR, urine.