TABLE 2

Candida auris antifungal MIC ranges determined by the CLSI broth microdilution reference method

DrugTentativea resistance breakpointsMIC range (μg/ml)b
MICMIC50MIC90
Fluconazole≥320.12 to ≥64≥64≥64
VoriconazoleNA0.032 to 160.5 to 22 to 8
ItraconazoleNA0.032 to 20.06 to 0.50.25 to 1
PosaconazoleNA0.015 to 160.016 to 0.50.125 to 2
IsavuconazoleNA0.015 to 40.125 to 0.250.5 to 2
Anidulafungin≥40.015 to 160.125 to 0.50.5 to 1
Caspofungin≥20.03 to 160.25 to 11 to 2
Micafungin≥40.015 to 80.125 to 0.250.25 to 2
Amphotericin≥20.06 to 80.5 to 12 to 4