TABLE 4

Detection properties of the different tests by parasitemia for monospecific P. falciparum uPCR-positive infections (P. falciparum by reference B)a

TestParasitemia (no. of parasites/ml)bNo. of infections detected by parasitemia category (% of uPCR reference)c
Geometric mean (95% CI)Median (IQR)>100,000 p/ml10,000–100,000 p/ml1,000–10,000 p/ml100–1,000 p/ml<100 p/mlTotal
Lab uRDT3,019 (1,790–5094)2,939 (484–13,748)7 (100)17 (94)27 (87)24 (48)4 (11)79 (55)
Lab RDT11,352 (5,643–22,837)11,144 (4,377–52,429)7 (100)12 (67)15 (48)3 (6)1 (3)38 (27)
Microscopy19,132 (10,701–34,205)15,151 (6,919–54,225)7 (100)16 (89)12 (39)1 (2)0 (0)36 (25)
uPCR reference734 (481– 1,117)497 (90–5,506)7 (100)18 (100)31 (100)50 (100)37 (100)143 (100)
Field uRDT4,960 (2,657–9,260)6,764 (632–18,924)7 (100)15 (83)17 (57)14 (29)2 (6)55 (39)
Field RDT14,237 (4,659–43,509)15,229 (2,410–170,102)7 (100)7 (39)5 (17)3 (6)1 (3)23 (16)
uPCR reference742 (485–1135)493 (95–4,941)7 (100)18 (100)30 (100)49 (100)36 (100)140 (100)
  • a Corresponding graphs are presented in Fig. S2 in the supplemental material.

  • b 95% CI, 95% confidence interval; IQR, interquartile range.

  • c Parasitemia is given in the number of parasites per milliliter (p/ml).